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Search Results for " leukotriene c4 "

17

Compounds

Cat No. Product Name Synonyms Targets
T25687 Leukotriene C4 LTC4,Leukotriene C
Leukotriene C4 is the conjugation product of Leukotriene A4 and glutathione. It is the major arachidonic acid metabolite in human mast cells, macrophages, and antigen-sensitized lung tissue. It stimulates mucus secretion...
T37980 N-methyl Leukotriene C4 N-methyl Leukotriene C4
Produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets, leukotriene C4 (LTC4) is the parent cysteinyl leukotriene formed by the LTC4 synthase-catalyzed conjugation of glutathione t...
T37620 Leukotriene C4 methyl ester
Leukotriene C4 (LTC4) is the parent cysteinyl-leukotriene produced by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, and mast cells, and by transcellular met...
T37492 11-trans Leukotriene C4 11-trans Leukotriene C4
11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. LTC4 undergoes slow temperature-dependent isomerization to 11-trans LTC4 during storage. 11-trans LTC4 is produced in smaller amounts relative...
T16280 Nedocromil FPL 59002 Leukotriene Receptor , Prostaglandin Receptor , Histamine Receptor
Nedocromil (FPL 59002) inhibits the action or formation of multiple mediators. Which including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).
T14387 AZD9898 Leukotriene Receptor
AZD9898 is an inhibitor of leukotriene-C4 synthetase with an IC50 of 0.28 nM. AZD9898 can be used in studies about asthma. AZD9898 mitigates the GABA binding and hepatic toxicity signal.
T67959 Pirodomast Thrombin , Serine Protease
Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is weakly or ineffectively antagonistic to guinea pig bronchospas...
T71039 MDL-28753
MDL-28753 is an antagonist of leukotriene D4 and antagonist of leukotrine C4.
T13879 (S)-Verapamil hydrochloride (S)-(-)-Verapamil hydrochloride Calcium Channel
(S)-Verapamil hydrochloride is an inhibitor of leukotriene C4 (LTC4) and calcein transport by MRP1,and leads to the death of potentially resistant tumor cells.
T13165 TK05 Others
TK05 is a potent and selective leukotriene C4 synthase (LTC4S) inhibitor (IC50: 95 nM).
T10054 CI-949 Others
CI-949 is an allergic mediator release inhibitor, which inhibits leukotriene C4/D4 (LTC4/LTD4), histamine, and thromboxane B2 (TXB2) release (IC50s: 0.5 μM, 11.4 μM and 0.1 μM).
T37616 Leukotriene A4 methyl ester Leukotriene A4 methyl ester
Leukotriene A4 methyl ester can be converted into leukotriene C4 monomethyl ester catalyzed by the major alkaline cytosolic glutathione transferase in rat liver, which can be used in metabolism-related studies.
T19674 Verlukast MK 0679,MK-679,L 668,019,MK 679,L 668019,L-668,019
Verlukast is an (R)-enantiomer of MK-571 and a potent and selective LTD4 receptor antagonist. Verlukast showed [3H]leukotriene D4 binding in guinea-pig (IC50 = 3.1 +/- 0.5 nM) and human (IC50 = 8.0 +/- 3.0 nM) lung homog...
TN2511 Britannilactone diacetate 1,6-O,O-Diacetylbritannilactone IL Receptor , PARP , ROS , MAPK , Caspase , JAK , JNK , STAT
1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airway disease as a lead compound. OODBL has anti-asthmatic acti...
T37505 MCTR1 MCTR1
Maresin conjugates in tissue regeneration 1 (MCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is ...
T37506 MCTR2 MCTR2
Maresin conjugates in tissue regeneration 2 (MCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is ...
T37507 MCTR3 MCTR3
Maresin conjugates in tissue regeneration 3 (MCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages. DHA is oxidized to maresin 1 , which is converted to MCTR1 by glutat...
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